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Neuropsychiatric Systemic Lupus Erythematosus

MedGen UID:
199870
•Concept ID:
C0752335
•
Disease or Syndrome

Professional guidelines

PubMed

Neuropsychiatric Systemic Lupus Erythematosus: Molecules Involved in Its Imunopathogenesis, Clinical Features, and Treatment.
Justiz-Vaillant AA, Gopaul D, Soodeen S, Arozarena-Fundora R, Barbosa OA, Unakal C, Thompson R, Pandit B, Umakanthan S, Akpaka PE
Molecules 2024 Feb 6;29(4) doi: 10.3390/molecules29040747. PMID: 38398500Free PMC Article
Advances in the diagnosis, pathogenesis and treatment of neuropsychiatric systemic lupus erythematosus.
Moore E, Huang MW, Putterman C
Curr Opin Rheumatol 2020 Mar;32(2):152-158. doi: 10.1097/BOR.0000000000000682. PMID: 31895125Free PMC Article
Management of Neuropsychiatric Systemic Lupus Erythematosus: Current Approaches and Future Perspectives.
Magro-Checa C, Zirkzee EJ, Huizinga TW, Steup-Beekman GM
Drugs 2016 Mar;76(4):459-83. doi: 10.1007/s40265-015-0534-3. PMID: 26809245Free PMC Article

Recent clinical studies

Etiology

Therapeutic strategies and outcomes in neuropsychiatric systemic lupus erythematosus: an international multicentre retrospective study.
Bortoluzzi A, Fanouriakis A, Silvagni E, Appenzeller S, Carli L, Carrara G, Cauli A, Conti F, Costallat LTL, De Marchi G, Doria A, Fredi M, Franceschini F, Garaffoni C, Hanly JG, Mosca M, Murphy E, Piga M, Quartuccio L, Scirè CA, Tomietto P, Truglia S, Zanetti A, Zen M, Bertsias G, Govoni M
Rheumatology (Oxford) 2024 Oct 1;63(10):2711-2720. doi: 10.1093/rheumatology/keae119. PMID: 38402539
Juvenile Neuropsychiatric Systemic Lupus Erythematosus: Identification of Novel Central Neuroinflammation Biomarkers.
Labouret M, Costi S, Bondet V, Trebossen V, Le Roux E, Ntorkou A, Bartoli S, Auvin S, Bader-Meunier B, Baudouin V, Corseri O, Dingulu G, Ducrocq C, Dumaine C, Elmaleh M, Fabien N, Faye A, Hau I, Hentgen V, Kwon T, Meinzer U, Ouldali N, Parmentier C, Pouletty M, Renaldo F, Savioz I, Rozenberg F, Frémond ML, Lepelley A, Rice GI, Seabra L, Benoist JF, Duffy D, Crow YJ, Ellul P, Melki I
J Clin Immunol 2023 Apr;43(3):615-624. Epub 2022 Dec 5 doi: 10.1007/s10875-022-01407-1. PMID: 36469191Free PMC Article
Epidemiology, characterization, and diagnosis of neuropsychiatric events in systemic lupus erythematosus.
de Amorim JC, Frittoli RB, Pereira D, Postal M, Dertkigil SSJ, Reis F, Costallat LT, Appenzeller S
Expert Rev Clin Immunol 2019 Apr;15(4):407-416. Epub 2019 Jan 14 doi: 10.1080/1744666X.2019.1564040. PMID: 30632405
A Brain Ring-Enhancing Lesion.
Lindsey M, Harrison N, Bridges J, Blossom J, Kishore S, Majithia V
Am J Med Sci 2018 Sep;356(3):304-308. Epub 2018 Feb 2 doi: 10.1016/j.amjms.2018.01.009. PMID: 30049410
EULAR recommendations for the management of systemic lupus erythematosus with neuropsychiatric manifestations: report of a task force of the EULAR standing committee for clinical affairs.
Bertsias GK, Ioannidis JP, Aringer M, Bollen E, Bombardieri S, Bruce IN, Cervera R, Dalakas M, Doria A, Hanly JG, Huizinga TW, Isenberg D, Kallenberg C, Piette JC, Schneider M, Scolding N, Smolen J, Stara A, Tassiulas I, Tektonidou M, Tincani A, van Buchem MA, van Vollenhoven R, Ward M, Gordon C, Boumpas DT
Ann Rheum Dis 2010 Dec;69(12):2074-82. Epub 2010 Aug 19 doi: 10.1136/ard.2010.130476. PMID: 20724309

Diagnosis

Neuropsychiatric Systemic Lupus Erythematosus: Molecules Involved in Its Imunopathogenesis, Clinical Features, and Treatment.
Justiz-Vaillant AA, Gopaul D, Soodeen S, Arozarena-Fundora R, Barbosa OA, Unakal C, Thompson R, Pandit B, Umakanthan S, Akpaka PE
Molecules 2024 Feb 6;29(4) doi: 10.3390/molecules29040747. PMID: 38398500Free PMC Article
Biomarkers for systemic lupus erythematosus - a focus on organ damage.
Ding H, Shen Y, Hong SM, Xiang C, Shen N
Expert Rev Clin Immunol 2024 Jan-Jun;20(1):39-58. Epub 2023 Sep 15 doi: 10.1080/1744666X.2023.2260098. PMID: 37712757
Advances in the diagnosis, pathogenesis and treatment of neuropsychiatric systemic lupus erythematosus.
Moore E, Huang MW, Putterman C
Curr Opin Rheumatol 2020 Mar;32(2):152-158. doi: 10.1097/BOR.0000000000000682. PMID: 31895125Free PMC Article
Management of Neuropsychiatric Systemic Lupus Erythematosus: Current Approaches and Future Perspectives.
Magro-Checa C, Zirkzee EJ, Huizinga TW, Steup-Beekman GM
Drugs 2016 Mar;76(4):459-83. doi: 10.1007/s40265-015-0534-3. PMID: 26809245Free PMC Article
EULAR recommendations for the management of systemic lupus erythematosus with neuropsychiatric manifestations: report of a task force of the EULAR standing committee for clinical affairs.
Bertsias GK, Ioannidis JP, Aringer M, Bollen E, Bombardieri S, Bruce IN, Cervera R, Dalakas M, Doria A, Hanly JG, Huizinga TW, Isenberg D, Kallenberg C, Piette JC, Schneider M, Scolding N, Smolen J, Stara A, Tassiulas I, Tektonidou M, Tincani A, van Buchem MA, van Vollenhoven R, Ward M, Gordon C, Boumpas DT
Ann Rheum Dis 2010 Dec;69(12):2074-82. Epub 2010 Aug 19 doi: 10.1136/ard.2010.130476. PMID: 20724309

Therapy

Therapeutic strategies and outcomes in neuropsychiatric systemic lupus erythematosus: an international multicentre retrospective study.
Bortoluzzi A, Fanouriakis A, Silvagni E, Appenzeller S, Carli L, Carrara G, Cauli A, Conti F, Costallat LTL, De Marchi G, Doria A, Fredi M, Franceschini F, Garaffoni C, Hanly JG, Mosca M, Murphy E, Piga M, Quartuccio L, Scirè CA, Tomietto P, Truglia S, Zanetti A, Zen M, Bertsias G, Govoni M
Rheumatology (Oxford) 2024 Oct 1;63(10):2711-2720. doi: 10.1093/rheumatology/keae119. PMID: 38402539
Neuropsychiatric Systemic Lupus Erythematosus: Molecules Involved in Its Imunopathogenesis, Clinical Features, and Treatment.
Justiz-Vaillant AA, Gopaul D, Soodeen S, Arozarena-Fundora R, Barbosa OA, Unakal C, Thompson R, Pandit B, Umakanthan S, Akpaka PE
Molecules 2024 Feb 6;29(4) doi: 10.3390/molecules29040747. PMID: 38398500Free PMC Article
Choroid plexus and perivascular space enlargement in neuropsychiatric systemic lupus erythematosus.
Gueye M, Preziosa P, Ramirez GA, Bozzolo EP, Canti V, Margoni M, Meani A, Moiola L, Rovere-Querini P, Manfredi AA, Filippi M, Rocca MA
Mol Psychiatry 2024 Feb;29(2):359-368. Epub 2023 Nov 30 doi: 10.1038/s41380-023-02332-4. PMID: 38036603
Management of Neuropsychiatric Systemic Lupus Erythematosus: Current Approaches and Future Perspectives.
Magro-Checa C, Zirkzee EJ, Huizinga TW, Steup-Beekman GM
Drugs 2016 Mar;76(4):459-83. doi: 10.1007/s40265-015-0534-3. PMID: 26809245Free PMC Article
Neuropsychiatric Systemic Lupus Erythematosus in Children.
Soybilgic A
Pediatr Ann 2015 Jun;44(6):e153-8. doi: 10.3928/00904481-20150611-11. PMID: 26114371

Prognosis

Biomarkers for systemic lupus erythematosus - a focus on organ damage.
Ding H, Shen Y, Hong SM, Xiang C, Shen N
Expert Rev Clin Immunol 2024 Jan-Jun;20(1):39-58. Epub 2023 Sep 15 doi: 10.1080/1744666X.2023.2260098. PMID: 37712757
Neuropsychiatric Systemic Lupus Erythematosus in Older Adults: Diagnosis and Management.
Tayer-Shifman OE, Bingham KS, Touma Z
Drugs Aging 2022 Feb;39(2):129-142. Epub 2021 Dec 16 doi: 10.1007/s40266-021-00911-0. PMID: 34913146
Advances in the diagnosis, pathogenesis and treatment of neuropsychiatric systemic lupus erythematosus.
Moore E, Huang MW, Putterman C
Curr Opin Rheumatol 2020 Mar;32(2):152-158. doi: 10.1097/BOR.0000000000000682. PMID: 31895125Free PMC Article
Neuropsychiatric Systemic Lupus Erythematosus in Children.
Soybilgic A
Pediatr Ann 2015 Jun;44(6):e153-8. doi: 10.3928/00904481-20150611-11. PMID: 26114371
EULAR recommendations for the management of systemic lupus erythematosus with neuropsychiatric manifestations: report of a task force of the EULAR standing committee for clinical affairs.
Bertsias GK, Ioannidis JP, Aringer M, Bollen E, Bombardieri S, Bruce IN, Cervera R, Dalakas M, Doria A, Hanly JG, Huizinga TW, Isenberg D, Kallenberg C, Piette JC, Schneider M, Scolding N, Smolen J, Stara A, Tassiulas I, Tektonidou M, Tincani A, van Buchem MA, van Vollenhoven R, Ward M, Gordon C, Boumpas DT
Ann Rheum Dis 2010 Dec;69(12):2074-82. Epub 2010 Aug 19 doi: 10.1136/ard.2010.130476. PMID: 20724309

Clinical prediction guides

Therapeutic strategies and outcomes in neuropsychiatric systemic lupus erythematosus: an international multicentre retrospective study.
Bortoluzzi A, Fanouriakis A, Silvagni E, Appenzeller S, Carli L, Carrara G, Cauli A, Conti F, Costallat LTL, De Marchi G, Doria A, Fredi M, Franceschini F, Garaffoni C, Hanly JG, Mosca M, Murphy E, Piga M, Quartuccio L, Scirè CA, Tomietto P, Truglia S, Zanetti A, Zen M, Bertsias G, Govoni M
Rheumatology (Oxford) 2024 Oct 1;63(10):2711-2720. doi: 10.1093/rheumatology/keae119. PMID: 38402539
Choroid plexus and perivascular space enlargement in neuropsychiatric systemic lupus erythematosus.
Gueye M, Preziosa P, Ramirez GA, Bozzolo EP, Canti V, Margoni M, Meani A, Moiola L, Rovere-Querini P, Manfredi AA, Filippi M, Rocca MA
Mol Psychiatry 2024 Feb;29(2):359-368. Epub 2023 Nov 30 doi: 10.1038/s41380-023-02332-4. PMID: 38036603
Brain-reactive autoantibodies in neuropsychiatric systemic lupus erythematosus.
Cocco C, Manca E, Corda G, Angioni MM, Noli B, Congia M, Loy F, Isola M, Chessa E, Floris A, Lorefice L, Saba L, Mathieu A, Ferri GL, Cauli A, Piga M
Front Immunol 2023;14:1157149. Epub 2023 Jun 13 doi: 10.3389/fimmu.2023.1157149. PMID: 37383228Free PMC Article
Neuropsychiatric Systemic Lupus Erythematosus in Older Adults: Diagnosis and Management.
Tayer-Shifman OE, Bingham KS, Touma Z
Drugs Aging 2022 Feb;39(2):129-142. Epub 2021 Dec 16 doi: 10.1007/s40266-021-00911-0. PMID: 34913146
Advances in the diagnosis, pathogenesis and treatment of neuropsychiatric systemic lupus erythematosus.
Moore E, Huang MW, Putterman C
Curr Opin Rheumatol 2020 Mar;32(2):152-158. doi: 10.1097/BOR.0000000000000682. PMID: 31895125Free PMC Article

Recent systematic reviews

Machine Learning for Diagnosis of Systemic Lupus Erythematosus: A Systematic Review and Meta-Analysis.
Zhou Y, Wang M, Zhao S, Yan Y
Comput Intell Neurosci 2022;2022:7167066. Epub 2022 Nov 22 doi: 10.1155/2022/7167066. PMID: 36458233Free PMC Article
Relevant domains and outcome measurement instruments in neuropsychiatric systemic lupus erythematosus: a systematic literature review.
Silvagni E, Chessa E, Bergossi F, D'Amico ME, Furini F, Guerrini G, Cauli A, Scirè CA, Bertsias G, Govoni M, Piga M, Bortoluzzi A
Rheumatology (Oxford) 2021 Dec 24;61(1):8-23. doi: 10.1093/rheumatology/keab324. PMID: 33788917
MOG-IgG-associated disorder and systemic lupus erythematosus disease: Systematic review.
Caroline Breis L, Antônio Machado Schlindwein M, Pastor Bandeira I, Machiavelli Fontana T, Fiuza Parolin L, Weingrill P, Kleinpaul Vieira RG, Vinícius Magno Gonçalves M
Lupus 2021 Mar;30(3):385-392. Epub 2020 Dec 8 doi: 10.1177/0961203320978514. PMID: 33290135
Response to placebo in non-renal, non-neuropsychiatric systemic lupus erythematosus: a systematic review and pooled analysis.
Tselios K, Wakani L, Gladman DD, Su J, Urowitz MB
Rheumatology (Oxford) 2021 Jan 5;60(1):73-80. doi: 10.1093/rheumatology/keaa655. PMID: 33140092
Autoantibodies involved in neuropsychiatric manifestations associated with systemic lupus erythematosus: a systematic review.
Sciascia S, Bertolaccini ML, Roccatello D, Khamashta MA, Sanna G
J Neurol 2014 Sep;261(9):1706-14. Epub 2014 Jun 21 doi: 10.1007/s00415-014-7406-8. PMID: 24952022

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